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ADAMTS5 PROTEIN
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DeCS
Descriptor
English
:
ADAMTS5 Protein
Descriptor
Spanish
:
Proteína ADAMTS5
Descriptor
Portuguese
:
Proteína ADAMTS5
Synonyms
English
:
A Disintegrin And Metalloproteinase With Thrombospondin Motifs 5 Protein
ADAMTS-5 Protein
ADAMTS11 Protein
ADAMTS5 Protease
Aggrecanase-2
ADAMTS 5 Protein
Aggrecanase 2
Tree Number:
D08.811.277.656.675.374.102.500.875
D09.400.430.500.500.875
D12.776.395.033.500.875
D12.776.860.300.085.875
Definition
English
:
An ADAMTS protease that contains two C-terminal
thrombospondin
(TS) motifs. It functions primarily as an aggrecanase, cleaving AGGRECAN in
CARTILAGE
, and may be involved in the destruction of aggrecan in
ARTHRITIS.
History Note
English
:
2017
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56489
Unique Identifier:
D000071116
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS